ISRG vs SYK
Intuitive Surgical (ISRG) and Stryker (SYK) compared side by side. Intuitive Surgical (ISRG) is larger, with a market cap of $159.8B versus $117.8B for Stryker, about 1.4 times the size. On trailing earnings, SYK is cheaper at 31.8x versus 54.7x for ISRG.
Head to head
| Metric | ISRG | SYK |
|---|---|---|
| Market cap | $159.8B | $117.8B |
| P/E (TTM) | 54.7x | 31.8x |
| Forward P/E | 36.4x | 18.4x |
| Revenue (TTM) | $11.6B | $25.8B |
| Revenue growth | 21.7% | 9.4% |
| Gross margin | 66.6% | 65.6% |
| Operating margin | 33.3% | 27.0% |
| Free cash flow | $3.2B | $4.7B |
| Dividend yield | None | 1.15% |
| 1-year return | -18.0% | -18.9% |
| 5-year return (annual) | +5.8% | +3.3% |
| Max drawdown | -82% | -59% |
| FI Handbook grade | B | B- |
Highlighted: the stronger figure on metrics where higher or lower is clearly better.
Growth of $10,000 (5 years, price only)
ISRG vs SYK FAQ
Which is bigger, ISRG or SYK?
Intuitive Surgical (ISRG) is larger, with a market cap of $159.8B versus $117.8B for Stryker, about 1.4 times the size.
Is ISRG or SYK cheaper?
On trailing earnings, SYK is cheaper at 31.8x versus 54.7x for ISRG. A lower P/E can reflect slower expected growth, so compare growth and margins too.
Which stock performed better over the past year, ISRG or SYK?
ISRG returned -18.0% over the past year including dividends, versus -18.9% for SYK, through October 23, 2026.
Which pays a higher dividend, ISRG or SYK?
SYK yields 1.15%; ISRG does not pay a dividend.
Full pages: Intuitive Surgical · Stryker